ACRES in association with iiBIG present:

SYNERGY: Where Clinical Research, Innovation, Collaboration <br>
                  and Systems Thinking Come Together!

OCTOBER 1-2, 2015

OMNI BOSTON

BOSTON, MA

Agenda

SYNERGY will abandon a simple “talking-heads” content-flow model in favor of an interactive, personally engaging, solution-generating model—every attendee will be a participating thought-leader! Session facilitators are currently being confirmed and the SYNERGY agenda will be updated periodically in the coming weeks. Please check back regularly for updates. In the meantime, for more information please contact the conference organizer:

Mary Tobin
Mary Tobin, Ph.D., Special Advisor to the President and CEO, ACRES
Email: mtobin@acresglobal.net



Day ONE – THURSDAY, October 1, 2015

11:00 – 5:00
Registration Open


11:45 – 12:00
Welcoming Remarks & Introductions (S01)

Mary Tobin
Mary Tobin, Ph.D., Special Advisor to the President and CEO,
ACRES

Don Buford
Don Buford, CEO,
iiBIG


12:00 – 1:00
Keynote Adress

Briggs Morrison
Briggs W. Morrison, M.D., ‪CEO, Syndax Pharmaceuticals
& Managing Director, MPM Capital


1:00 – 1:30
Conference Overview (S02)
Systems Thinking: A Discipline for Seeing Wholes Rather Than Just the Pieces

  • A system is much more than the sum of its parts; appreciating the connectedness and inter-dependence of the components allows one to envision new opportunities

Greg KoskiGreg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES (Alliance for Clinical Research Excellence & Safety) - Boston, MA
Senior Scientist, James Mongan Institute for Health Policy
Associate Professor of Anesthesia, Massachusetts General Hospital, Harvard Medical School


1:30 – 2:30
Plenary Panel Discussion (S03)
Misadventures in Pharmaland: Dividing an Elephant does not Make Two Elephants

  • All components of a system are inter-related and inter-dependent; changing one component may profoundly impact others in unexpected ways, sometimes leading to failure
  • Examples where the lack of systems thinking contributed to a failed outcome

Brendan Buckley
Prof. Brendan M Buckley MD DPhil FRCPI, Chief Medical Officer,
ICON

Rebecca Daniels Kush
Rebecca Daniels Kush, Ph.D., Founder, President and CEO,
Clinical Data Interchange Standards Consortium (CDISC)

Leslie Platt
Leslie Platt, J.D., Senior Advisor,
MITRE Health & Human Services

Facilitator:
Greg Koski
Greg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES


2:30 – 3:00
Refreshments & Networking


3:00 – 4:00
Plenary Presentation (S04)
From Complexity to Synergy: Why Silos Present Barriers to Innovation, Collaboration and Change

  • Participants introduced to the most appropriate system thinking concepts applicable to clinical research
  • Participants can see where the individual components of clinical research process fit into an integrated global system.

Greg Koski
Greg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES

Kimberly Warren
Kimberly Warren, Director, HHS Portfolio, CAMH FFRDC, Systems Engineering and AI,
The MITRE Corporation


4:00 – 5:20
Plenary Cross-Panel Discussion with Attendees (S05)
Through the Retrospectoscope: Learning from Experience to Build a Better Future

  • Panelists discuss how Systems Thinking could have positively impacted the outcome of the Failure Stories.
  • Attendees reflect and react: How they might think differently today to act differently tomorrow

Brendan M Buckley
Prof. Brendan M Buckley MD DPhil FRCPI, Chief Medical Officer,
ICON

ebecca Daniels Kush
Rebecca Daniels Kush, Ph.D., Founder, President and CEO,
Clinical Data Interchange Standards Consortium (CDISC)

Leslie Platt
Leslie Platt, J.D., Senior Advisor,
MITRE Health & Human Services

Facilitators:
Greg Koski
Greg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES

Kimberly Warren
Kimberly Warren, Director, HHS Portfolio, CAMH FFRDC, Systems Engineering and AI,
The MITRE Corporation


5:20 – 5:30
Wrap-Up Day 1 (S06)

Mary Tobin
Mary Tobin, Ph.D., Special Advisor to the President and CEO,
ACRES


5:30
End of Day One


5:30 – 7:00
Gala Networking Reception


Day TWO – FRIDAY, October 2, 2015

8:00 – 8:30
Networking & Registration


8:30 – 9:00
Opening Remarks - Day 2 (S07)
Finding Systems Solutions: “Seeing Relationships Among Research Components”

Greg KoskiGreg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES (Alliance for Clinical Research Excellence & Safety) - Boston, MA
Senior Scientist, James Mongan Institute for Health Policy
Associate Professor of Anesthesia, Massachusetts General Hospital, Harvard Medical School


9:00 – 9:45
Cross-Sector Panel Discussion with Audience Collaboration (S08)
PATIENT EMPOWERMENT AND ENGAGEMENT

Jack Whelan
Jack Whelan, Author, Lecturer, Research Advocate -
Cancer Warrior and Survivor

Kristina D. Sheridan
Kristina D. Sheridan, Associate Dept. Head, Emerging Technologies, Systems Engineering Technical Cente, The MITRE Corporation

Bonnie A. Brescia
Bonnie A. Brescia, Founding Principal,
BBK Worldwide

Facilitators:
Greg Koski
Greg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES

Mary Tobin
Mary Tobin, Ph.D., Special Advisor to the President and CEO,
ACRES


9:45 – 10:45
Cross-Sector Panel Discussion with Audience Collaboration (S09)
PROTOCOL/TRIAL DESIGN

Susan S. Ellenberg
Susan S. Ellenberg, Ph.D., Professor of Biostatistics, Perelman School of Medicine,
University of Pennsylvania

Jeffrey Wendel
Jeffrey Wendel, MBA, President and Chief Executive Officer,
Chesapeake IRB

Gunther Winkler
Gunther Winkler, Ph.D., Founder and CEO,
Biometheus

Facilitator:
Greg Koski
Greg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES


10:45 – 11:15
Refreshments & Networking


11:15 – 12:15
Cross-Sector Panel Discussion with Audience Collaboration (S10)
TECHNOLOGY

Peter Alterman
Peter Alterman, PhD, COO,
SAFE-BioPharma Association

Cerdi Beltre
Cerdi Beltre, Director of Data Strategy and Business Development,
Merge eClinical

Rob Curry
Rob Curry, Vice President, Operational Excellence Services,
Covance

Daniel O’Connor
Daniel O’Connor, J.D., President & Chief Business Officer,
InnovoCommerce LLC

Facilitators:
Greg Koski
Greg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES

Scott Lowry
Scott Lowry, Founder and CEO,
HealthIDx


12:15 – 1:15
Luncheon & Networking


1:15 – 3:15
Cross-Sector Panel Discussion with Audience Collaboration (S11)
ROUNDTABLE: Achieving Synergy: Just Do It!

All panelists from previous topic areas will discuss:

Explore:

  • Challenges to accepting and implementing systems thinking for each topic
  • Strategies and tactics for countering Challenges
  • Suggestions for Plan of Action and Next Steps
    • Technology (including Platform, Portals/Cloud and Dataflow/analytics)
    • Patient Empowerment and Engagement (i.e., real 'patient-centricity')
    • Protocol/Trial Design (e.g., complexity of trials)

Facilitators:
Greg Koski
Greg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES

Mary Tobin
Mary Tobin, Ph.D., Special Advisor to the President and CEO,
ACRES

Matthew Whalen
Matthew D Whalen, PhD, COO,
ACRES


3:15 – 3:45
Refreshments & Networking


3:45 – 4:45
Closing Keynote Address (S12)

Brendan Buckley
Prof. Brendan M Buckley MD DPhil FRCPI, Chief Medical Officer,
ICON


4:45 – 5:00
Conference Wrap-up (S13)

Mary Tobin
Mary Tobin, Ph.D., Special Advisor to the President and CEO,
ACRES

Greg Koski
Greg Koski, Ph.D., M.D., Chairman, Co-Founder, President & CEO,
ACRES


5:00
EVENT CONCLUDES

REGISTER NOW
Event Details
What: SYNERGY
Why: Where Clinical Research, Innovation, Collaboration and Systems Thinking Come Together!
When:
Where: OMNI Boston
Boston, Massachusetts